Anti-Human Phosphodiesterase V (PDE-5)
Anti-Human Phosphodiesterase V (PDE-5)
Product No.: P164
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Clone 29.29 Target Phosphodiesterase V Formats AvailableView All Product Type Monoclonal Antibody Alternate Names PDE-5 Isotype IgG1 Applications WB |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.5 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient RRIDAB_2831533 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Anti-Human Phosphodiesterase V (Phosphodiesterase V) (Clone 29.29) recognizes an epitope on Human Phosphodiesterase V. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Phosphodiesterases (PDEs) are a superfamily of enzymes that degrade the intracellular second messengers cyclic AMP and cyclic GMP. These enzymes are essential regulators of cyclic nucleotide signaling with diverse physiological functions. PDEs are drug targets for the treatment of disease states including heart failure, depression, asthma, inflammation and erectile dysfunction. Of the 12 PDE gene families, cGMP specific PDE5 carries out the principal cGMP hydrolyzing activity.1,2 Antigen DetailsResearch Area Apoptosis . Cell Biology . Immunology References & Citations1. Piazza, G. et al. (2001) Cancer Research 61:3961-3968 2. Sung, BJ. et al. (2003) Nature 425:98-102 Technical Protocols |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
