Anti-Human TSH-ß [Clone 155] — Purified
Anti-Human TSH-ß [Clone 155] — Purified
Product No.: T114
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Clone 155 Target Thyroid Stimulating Hormone Beta Formats AvailableView All Product Type Monoclonal Antibody Alternate Names HCG, GPH, GPHA1, CGA, Thyrotropin Isotype Mouse IgG |
Data
TSH LOD GraphThe attached graph shows that the gold conjugate (CG) antibody (T114) paired with the nitrocellulose membrane (NCM) antibody (T102) exhibits a strong, broad-range dose-response for human. The data supports an estimated Limit of Detection (LoD) of ≤125 μlU/mL from recombinant TSH (rhTSH) samples.
TSH LFA ImageThe TSH Lateral Flow Assay image shows a clear detection and visible signal increase at the test line, starting at the 500 μlU/mL concentration of rhTSH and strengthening up to 2000 μlU/mL, while the control line remains intensely positive across all concentrations. The match pair used to generate this data was Leinco detection antibody SKU T114 and capture antibody SKU T102.
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified Recombinant Human TSH-β (>98%) Product Concentration ≥ 5.0 mg/ml Purity ≥95% by SDS Page Formulation This purified antibody is supplied in 0.05 M phosphate buffered saline (PBS), pH 7.2 - 7.4, containing 0.1% sodium azide. as a preservative. State of Matter Liquid Storage and Handling This Purified Antibody is stable when stored at 2-8°C. Do not freeze. Cross Reactivity Paired with Leinco Prod. No. T100, Clone No. 154: TSH 100%, BhCG < 1%, ihCG < 1%, LH < 1%, FSH < 1%.
Paired with Leinco Prod. No. T103, Clone No. 171: TSH 100%, BhCG < 1%, ihCG ***%, LH < 1%, FSH < 1%.
*** inhibition of reaction
Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2737567 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Anti-Human Thyroid Stimulating Hormone Beta (TSH-β) (Clone 155) recognizes Human Thyroid Stimulating Hormone Beta. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Thyroid-stimulating hormone (TSH) is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3
References & Citations1. (1998) Bowen A
2. McPherson et al. (2000) Placenta 24: 941
3. Wenger, R H et al. (2003) Wildmann's Clinical Interpretation of Laboratory Tests
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Formats Available
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Prod No. | Description |
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T114 | |
H122 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
