Purified Recombinant Human TSH-β (>98%)
This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09% sodium azide.
Storage and Handling
This Purified Antibody is stable when stored at 2-8°C. Do not freeze.
Paired with Leinco Prod. No. T102, Clone No. 195: TSH 100%, BhCG < 1%, ihCG < 1%, LH <1%, FSH < 1%.
Country of Origin
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Mouse Anti-Human Thyroid Stimulating Hormone Beta (TSH-β) (Clone 183) recognizes Human Thyroid Stimulating Hormone Beta. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3
References & Citations
1. (1998) Bowen A 2. McPherson et al. (2000) Placenta 24: 941 3. Wenger, R H et al. (2003) Wildmann's Clinical Interpretation of Laboratory Tests
Products are for research use only. Not for use in diagnostic or therapeutic procedures.