Anti-Human TRAIL (CT)

Anti-Human TRAIL (CT)

Product No.: T202

[product_table name="All Top" skus="T202"]

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Target
TNF-Related Apoptosis-Inducing Ligand
Product Type
Polyclonal Antibody
Alternate Names
TNFSF10, APO2L, Apo-2L, CD253, TL2
Applications
IHC FFPE
,
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:T205
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human TNF-Related Apoptosis-Inducing Ligand (TRAIL) recognizes an epitope near the C-terminus of Human TRAIL. This polyclonal antibody was purified using affinity chromatography.
Background
TNF-related apoptosis-inducing ligand (TRAIL) belongs to the tumor necrosis factor family and activates rapid apoptosis in tumor cells, and binds to the death-signaling receptor DR4.1 TRAIL is a potential tumor specific cancer therapeutic agent, since it selectively induces apoptosis in transformed versus normal cells.2

Antigen Details

References & Citations

1. Ashkenazi , A. et al. (1997) Science 227: 818
2. Romeo, G. et al. (2005) Current Pharmaceutical Design 11: 933
IHC FFPE
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.