Anti-Human TRAIL Receptor-1 (NT)

PN:D278

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

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Rabbit Anti-Human TNF-Related Apoptosis Inducing Ligand Receptor-1 (TRAIL R-1) recognizes Human TRAIL R-1. This polyclonal antibody was purified using affinity chromatography.

Tumor necrosis factor-related apoptosis-inducing ligand Receptor 1 (TRAIL-R1) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.¹ The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.²

1. Yoo, NJ. et al. (2001) Oncogene 20: 399
2. Eberle, J. et al. (2005) J Investigative Dermatol. 125: 1010
3. Rimm, D. et al. (2005) Clin Cancer Research 11