Anti-KLK4 Antibody (56237)

Product No.: 56237

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Target
KLK4
Product Type
Polyclonal
Alternate Names
EC 3.4.21.-, Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Prostase, Serine protease 17
Isotype
Rabbit
Applications
WB

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Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
Peptide corresponding to aa 242-254 of human KLK4 protein.
Product Concentration
Lot Specific
Formulation
PBS, pH 7.4 with 0.02% sodium azide
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 39 kD is detected.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Polyclonal Antibody specific to KLK4
Background
KLK4 (also known as KLK-L1) is one of the many kallikrein serine proteases associated with carcinogenesis. KLK4 is upregulated by androgens and progestins and has been associated with prostate and breast cancers and possibly with other cancers.

Antigen Details

Function
Has a major role in enamel formation (PubMed:15235027). Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity). {UniProtKB:Q9Z0M1, PubMed:15235027}.
NCBI Gene Bank ID
UniProt.org
Research Area
Cancer Research

References & Citations

General Western Blot Protocol
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.