Anti-KLK4 Antibody (56237)
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Rabbit Immunogen Peptide corresponding to aa 242-254 of human KLK4 protein. Product Concentration Lot Specific Formulation PBS, pH 7.4 with 0.02% sodium azide State of Matter Liquid Product Preparation Purified by immunoaffinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 39 kD is detected. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to KLK4 Background KLK4 (also
known as KLK-L1) is one of the many
kallikrein serine proteases associated
with carcinogenesis. KLK4 is upregulated by androgens and progestins
and has been associated with prostate
and breast cancers and possibly with
other cancers. Antigen DetailsFunction Has a major role in enamel formation (PubMed:15235027). Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity). {UniProtKB:Q9Z0M1, PubMed:15235027}. NCBI Gene Bank ID UniProt.org Research Area Cancer Research References & CitationsTechnical Protocols |
