Anti-β lactamase Antibody (15721)
Anti-β lactamase Antibody (15721)
Product No.: 15721
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Clone 3E11.G3 Target β-Lactamase Formats AvailableView All Product Type Monoclonal Isotype Mouse IgG3 Applications ELISA |
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Antibody DetailsProduct DetailsReactive Species Enterobacter Cloacae Host Species Mouse Immunogen Type IV beta lactamase from Enterobacter cloacae. Product Concentration Lot Specific Formulation This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added. State of Matter Liquid Product Preparation Antibodies are purified by a multi-step process including the use of PEG purification chromatography. Storage and Handling Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco ELISA: use at 10-20ug/ml (optimized for immobilized beta-lactamase at 10ug/ml).
End users should determine optimal concentrations for their applications. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity This antibody recognizes Type IV beta-lactamase of Enterobacter cloacae. Background The beta-lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta-lactams are structurally related through the presence of a core beta-lactam ring. Bacterial resistance to beta-lactams continues to increase, primarily due to microbial production of beta-lactamases. Beta-lactamases catalyze the hydrolysis of the betalactam bond which destroys anti-bacterial activity. Bacteria the produce TEM- or SHV-type betalactamases have point mutations in structural genes that have extended the substrate specificity of these beta-lactamases. As a result, many of the beta-lactamase-producing Gram-negative bacteria have become multi-drug resistant. Beta-lactamase from Enterobacter cloacae is a serine beta-lactamase with substrate specificity for cephalosporins. UniProt.org Research Area Enzymes References & CitationsTechnical Protocols Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
