Anti-MMP 9 Antibody (29020)

Product No.: 29020

- -
- -
Target
MMP-9
Product Type
Polyclonal
Alternate Names
MMP-9, EC 3.4.24.35, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Isotype
Rabbit
Applications
WB

- -
- -
Select Product Size
- -
- -

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
Synthetic peptide corresponding to aa 540-552 of human MMP 9.
Product Concentration
Lot Specific
Formulation
PBS, pH 7.4 with 0.02% sodium azide
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
This antibody is stable for at least one (1) year at -20°C to -70°C. Store antibody in appropriate aliquots to avoid multiple freeze-thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
Immunoblotting: use at 1:500-1:1,000 dilution. A band at 92 kD is detected.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Polyclonal Antibody specific to MMP9
Background
MMP 9 is a matrix metalloproteinase produced by bone marrow derived cells and believed to contribute to skin carcinogenesis.

Antigen Details

Function
Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (PubMed:2551898, PubMed:1480034, PubMed:12879005). Could play a role in bone osteoclastic resorption (By similarity). Cleaves KiSS1 at a Gly-|-Leu bond (PubMed:12879005). Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed:32883094). Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (PubMed:1480034). Degrades fibronectin but not laminin or Pz-peptide. {UniProtKB:P41245, PubMed:12879005, PubMed:1480034, PubMed:2551898, PubMed:32883094}.
NCBI Gene Bank ID
UniProt.org
Research Area
Matrix/Metalloproteins

References & Citations

General Western Blot Protocol
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.