Anti-Mouse IFN-γ – Purified Functional Grade
Pricing & Details
Antibody DetailsProduct DetailsReactivity Species Mouse Host Species Rat Immunogen Purified Mouse IFN-γ Product Concentration 1.0 mg/ml Endotoxin Level <0.5 EU/mg as determined by the LAL method Purity >95% by SDS-PAGE and HPLC Formulation This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. Storage and Handling This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2830468 Applications and Recommended Usage? Quality Tested by Leinco ELISA Cap R4-6A2 antibody is useful as a detection antibody for a sandwich ELISA with a concentration range of 0.5-2.0 µg/ml as recommended. Other Applications Reported In Literature ? ELISPOT Cap ELISPOT Det N Additional Reported Applications For Relevant Conjugates ? IHC FF For specific conjugates of this clone, review literature for suggested application details. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone R4-6A2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3 Antigen DetailsProtein PubMed NCBI Gene Bank ID UniProt.org References & Citations1. Goeddel DV et al. (1982) Nature 298: 859
2. Wilson CB et al. (2007) Adv. Immunol. 96: 41
3. Hume DA et al. (2004) J Leukoc Biol. 75: 163 Technical Protocols |
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