Anti-Mouse Ly-6C (Activating) [Clone HK1.4] — Alexa Fluor® 488
Anti-Mouse Ly-6C (Activating) [Clone HK1.4] — Alexa Fluor® 488
Product No.: L261AF
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Clone HK1.4 Target Ly-6C Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Alternate Names Activating Isotype Rat IgG2c κ Applications FC |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Rat Immunogen Purified Recombinant Mouse Ly-6C (>98%) Product Concentration 0.2 mg/ml Formulation This Alexa Fluor® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Alexa Fluor® is a trademark of Life Technologies Corporation. State of Matter Liquid Storage and Handling This Alexa Fluor® 488 conjugate is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Excitation Laser Blue Laser (488 nm) Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rat Anti-Mouse Ly-6C (Clone HK1.4) recognizes an epitope on Mouse Ly-6C. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Ly-6C is a 14–17 kDa glycosylphosphatidylinositol (GPI)-anchored cell surface protein belonging to the Ly-6 superfamily. Expressed on subsets of monocytes, macrophages, endothelial cells, granulocytes, thymocytes, NK cells, and T lymphocytes, it is regulated by interferon-gamma and serves as a key marker for inflammatory monocyte lineage and memory CD8+ T cells. Antigen Distribution The antigen is found on some monocyte/macrophage populations, endothelial cells, thymocytes, NK-cells, T-cell subsets and 40% of bone marrow cells from all mouse strains tested. PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology References & Citations1. Havran, W. L. et al. (1988) J. Immunol. 140(4):1034 Technical Protocols Certificate of Analysis |
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L126 | |
L261 | |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
