Anti-Mouse γ/δ (TCR) – DyLight® 755

Anti-Mouse γ/δ (TCR) – DyLight® 755

Product No.: T605

[product_table name="All Top" skus="T605"]

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Clone
UC7-13D5
Target
γ/δ T-Cell Receptor
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
IgG
Applications
FC

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Antibody Details

Product Details

Reactive Species
Mouse
Host Species
Armenian Hamster
Product Concentration
0.5 mg/ml
Formulation
This DyLight<sup>®</sup> 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
The anti-mouse γ/δ T-cell receptor antibody reacts with all mouse TCR γ/δ heterodimers.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Antigen Distribution
γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.

Antigen Details

Research Area
Adaptive Immunity
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Immunology

References & Citations

Bluestone, J. A. et al. (1991) Immunol. Rev. 120:5
Flow Cytometry

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.