Anti-Mouse γ/δ (TCR) – DyLight® 594

Pricing & Details

Product No.T601
Clone
UC7-13D5
Protein
γ/δ T-Cell Receptor
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
Armenian Hamster
IgG
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
T601-50 µg
50 µg
$85.00
In stock
Max:
Min: 1
Step: 1
T601-100 µg
100 µg
$150.00
In stock
Max:
Min: 1
Step: 1
T601-200 µg
200 µg
$250.00
In stock
Max:
Min: 1
Step: 1

Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Armenian Hamster
Product Concentration
0.2 mg/ml
Formulation
This DyLight® 594 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Excitation Laser
Red Laser (590 nm)
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
The anti-mouse γ/δ T-cell receptor antibody reacts with all mouse TCR γ/δ heterodimers.
Antigen Distribution
γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

Antigen Details

Research Area
Adaptive Immunity
.
Immunology

References & Citations

Bluestone, J. A. et al. (1991) Immunol. Rev. 120:5
Flow Cytometry

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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