Anti-Mouse TLR7

Pricing & Details

Product No.T697
Protein
Toll-like Receptor 7
Formats AvailableView All
Product Type
Polyclonal Antibody
Applications
ELISA Cap
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
T697-20ug
20 µg
$95.00
In stock
Max:
Min: 1
Step: 1
T697-0.1 mg
0.1 mg
$440.00
In stock
Max:
Min: 1
Step: 1
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Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Rabbit
Immunogen
This TLR7 polyclonal antibody used a peptide immunogen located within amino acids 420 - 470 of TLR7.
Product Concentration
1.0 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Mouse Toll-like Receptor 7 (TLR7) recognizes Mouse TLR7. This polyclonal antibody was purified using affinity chromatography.
Background
The TLR family play a fundamental role in pathogen recognition and activation of innate immunity (1). They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity (2). TLR-3 is expressed primarily in dendritic cells of the placenta and pancreas where it can reside on both sides of the plasma membrane and in the endosomal compartment of the cells. It is also expressed in macrophages, micoglia and astrocytes, and is upregulated by IFNβ and LPS (4).

Antigen Details

NCBI Gene Bank ID

References & Citations

1. Hopkins, P. A. et al. (2005) Clin. Exp. Immunol. 140:395 2. Schroder, M. et al. (2005) Trends Immunol. 26:462 3. Farina, C. et al. (2005) J. Neuroimmunol. 159:12 4. de Bouteiller, O. et al. (2005) J. Biol. Chem. 280:38133
Elisa Sandwich Protocol
General Western Blot Protocol
Prod No.
Description
T697
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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