Anti-Propoxyphene (Clone PROP-4721)

Anti-Propoxyphene (Clone PROP-4721)

Product No.: P522

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Clone
PROP-4721
Target
Propoxyphene
Formats AvailableView All
Product Type
Hybridoma Monoclonal Antibody
Isotype
Mouse IgG1 κ
Applications
ELISA
,
Lateral Flow

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Select Product Size
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Antibody Details

Product Details

Product Concentration
≥1.0 mg/ml
Purity
>98% by SDS Page
Formulation
Formulated in 50mM sodium phosphate, 500mM sodium chloride, 10% glycerol, pH 7.8 and contains 0.05% sodium azide.
State of Matter
Liquid
Product Preparation
This monoclonal antibody is purified by Protein A chromatography.
Storage and Handling
2-8ºC
Regulatory Status
Research Use Only
Country of Origin
USA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Anti-Propoxyphene (Clone PROP-4721) is specific for propoxyphene.
Background
Propoxyphene, once prescribed as a pain reliever, is an opioid analgesic that has been withdrawn from the market due to safety concerns. Its primary method of action involves binding to opioid receptors in the brain and spinal cord, inhibiting the transmission of pain signals and altering the perception of pain. Despite its analgesic properties, propoxyphene was associated with cardiac toxicity, leading to its withdrawal from pharmaceutical use in 2010. Diagnostic testing for propoxyphene abuse typically involves urine analysis, as the drug and its metabolites can be detected in urine samples.

Antigen Details

Research Area
Drug of Abuse
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Matched Pair
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IVD Raw Material

References & Citations

1. Schiller EY, Goyal A, Mechanic OJ. Opioid Overdose. StatPearls. Treasure Island (FL): StatPearls Publishing; 2024.Link
Indirect Elisa Protocol
Lateral Flow

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.