Anti-Sin Nombre Virus (Hantavirus) (Clone: SNV-53)

Pricing & Details

Product No.LT552
Clone
SNV-53
Protein
Sin Nombre Virus
Formats AvailableView All
Product Type
Recombinant Monoclonal Antibody
Alternate Names
SNV
Isotype
Human IgG1
Applications
ELISA
,
N
Prod No.
Size
Price
Avail.
Qty
Add to cart
LT552-250 µg
250 µg
$390.00
Pre-order
Max:
Min: 1
Step: 1
LT552-1.0 mg
1.0 mg
$1,400.00
Pre-order
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Hantavirus
Sin Nombre
Virus
Expression Host
HEK-293
Immunogen
Sequenced from human survivors of Sin Nombre.
Product Concentration
≥ 5.0 mg/ml
Endotoxin Level
≤ 1.0 EU/mg as determined by the LAL method
Purity
≥95% monomer by analytical SEC
Formulation
This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Storage and Handling
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≥ -70°C. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Standard Overnight on Blue Ice.
Other Applications Reported In Literature ?
ELISA
N
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
SNV-53 specificity is directed against the surface glycoprotein spike.
Background
Hantavirus is an enveloped, negative-sensed, single-stranded RNA virus in the bunyavirus family1. “New World” hantaviruses (NWH) are found in the Americas and may cause hantavirus pulmonary syndrome (HPS)2. “Old World” hantaviruses (OWH) are found mostly in Europe and Asia and may cause hemorrhagic fever with renal syndrome. Each hantavirus serotype has a specific rodent host species and infection is spread by aerosolized urine, feces, saliva, or by rodent bites. Sin Nombre Virus (SNV), a NWH first isolated from rodents in the Southwestern United States, infects with a mortality rate of 50%1. The probability of survival for Syrian hamsters infected with SNV significantly increases when treated postinfection with the monoclonal antibody (mAb) SNV-533.

Antigen Details

Research Area
Infectious Disease
.
Sin Nombre
.
Viral

References & Citations

1. Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of High-Consequence Pathogens and Pathology (DHCPP), Link Text
2. Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of High-Consequence Pathogens and Pathology (DHCPP), Link Text
3. Engdahl TB, Kuzmina NA, Ronk AJ, et al. Cell Rep. 35(5):109086. 2021.
Elisa Sandwich Protocol

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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