Anti-West Nile Virus, NS1 (Clone WNV-3223)
Anti-West Nile Virus, NS1 (Clone WNV-3223)
Product No.: W122
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Clone WNV-3223 Target NS1 West Nile virus Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Alternate Names NS1, Non-structural protein 1, WNV Isotype Mouse IgG1 κ Applications ELISA , Lateral Flow |
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Antibody DetailsProduct DetailsReactivity Species West Nile Host Species Mouse Immunogen Culture virus infected cell lysate; strain NY99 Product Concentration ≥1.0 mg/ml Purity ≥90% by SDS PAGE Formulation Formulated in 0.015 M phosphate buffered saline (0.85% NaCl), pH 7.2 and contains 0.05% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by ion exchange chromatography. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2 – 8° C Wet Ice Applications and Recommended Usage? Quality Tested by Leinco ELISA, Lateral Flow Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-West Nile virus (Clone WNV-3223) is specific for WNV non-structural protein 1 (NS1). There is no cross-reactivity with other Flavivirus. Background West Nile Virus (WNV) is a mosquito-borne, enveloped, positive-stranded RNA
flavivirus1. Flavivirus nonstructural protein NS1 has been proposed as an antibody target
to avoid antibody-dependent enhancement2. NS1 is a 46-55 kDa glycoprotein that is
expressed as a dimer on the cell surface and as a soluble hexamer in the extracellular
space and in circulation during infection. WNV NS1 dimer consists of a ß-roll, wing, and
ß-ladder. Antigen DetailsResearch Area Category B Pathogens . Infectious Disease . Matched Pair . Viral . IVD Raw Material References & Citations1. Goo L, Debbink K, Kose N, et al. Nat Microbiol. 4(1):71-77. 2019. 2. Wessel AW, Doyle MP, Engdahl TB, et al. mBio. 12(5):e0244021. 2021. Technical Protocols Lateral Flow |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
