Recombinant Cardiac Troponin T (24102P)

Recombinant Cardiac Troponin T (24102P)

Product No.: 24102P

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Target
Cardiac Troponin T
Product Type
Recombinant Protein
Alternate Names
TnT
Isotype
Mouse IgG1
Applications
ELISA

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Select Product Size
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Purified human cardiac troponin T.
Product Concentration
Lot Specific
Purity
>90% for SDS PAGE
Formulation
Sterile-filtered colorless solution in 20mM Tris, pH 8.0, 10% glycerol. 
State of Matter
Liquid
Storage and Handling
Store at 4°C if entire vial will be used within 2-4 weeks. Store at -20°C for longer periods of time. For long term storage, addition of 0.1% human serum albumin or bovine serum albumin is recommended. Avoid multiple freeze- thaw cycles.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
Next Day 2-8°C
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MSDIEEVVEE YEEEEQEEAA VEEQEEAAEE DAEAEAETEE TRAEEDEEEE EAKEAEDGPM EESKPKPRSF MPNLVPPKIP DGERVDFDDI HRKRMEKDLN ELQALIEAHF ENRKKEEEEL VSLKDRIERR RAERAEQQRI RNEREKERQN RLAEERARRE EEENRRKAED EARKKKALSN MMHFGGYIQK TERKSGKRQT EREKKKKILA ERRKVLAIDH LNEDQLREKA KELWQSIYNL EAEKFDLQEK FKQQKYEINV LRNRINDNQK VSKTRGKAKV TGRWK
Additional Applications Reported In Literature ?
ELISA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Background
Troponin T (TnT) is the tropomyosin- binding subunit of the troponin complex which is situated on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentrations. Mutations in the TNNT2 gene are associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy and hypertrophic cardiomyopathy.
Function
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
NCBI Gene Bank ID
UniProt.org

References & Citations

Indirect Elisa Protocol

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.