Recombinant Cardiac Troponin T (24102P)
- -
- -
Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified human cardiac troponin T. Product Concentration Lot Specific Purity >90% for SDS PAGE Formulation Sterile-filtered colorless solution in 20mM Tris, pH 8.0, 10% glycerol. State of Matter Liquid Storage and Handling Store at 4°C if entire vial will be used within 2-4 weeks. Store at -20°C for longer periods of time. For long term storage, addition of 0.1% human serum albumin or bovine serum albumin is recommended. Avoid multiple freeze- thaw cycles. Regulatory Status Research Use Only Country of Origin USA Shipping Next Day 2-8°C Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSDIEEVVEE
YEEEEQEEAA VEEQEEAAEE DAEAEAETEE
TRAEEDEEEE EAKEAEDGPM EESKPKPRSF
MPNLVPPKIP DGERVDFDDI HRKRMEKDLN
ELQALIEAHF ENRKKEEEEL VSLKDRIERR
RAERAEQQRI RNEREKERQN RLAEERARRE
EEENRRKAED EARKKKALSN MMHFGGYIQK
TERKSGKRQT EREKKKKILA ERRKVLAIDH
LNEDQLREKA KELWQSIYNL EAEKFDLQEK
FKQQKYEINV LRNRINDNQK VSKTRGKAKV
TGRWK Additional Applications Reported In Literature ? ELISA Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionBackground Troponin T (TnT) is the tropomyosin- binding subunit of the troponin complex which is situated on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentrations. Mutations in the TNNT2 gene are associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy and hypertrophic cardiomyopathy. Function Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. NCBI Gene Bank ID UniProt.org References & CitationsTechnical ProtocolsCertificate of Analysis |
