DnaJ (11111P)
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Antibody DetailsProduct DetailsReactive Species Human Product Concentration Lot Specific Formulation Sterile-filtered colorless solution contains 20mM Tris buffer, pH 8.0, 2mM DTT, 0.2mM PMSF, and 10% glycerol. State of Matter Liquid Storage and Handling Although stable at 4°C for 4 weeks, product should be stored at or below -20°C. For long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended. Country of Origin USA Shipping Next Day 2-8°C Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Recombinant Human DnaJ Background Human Hsp40 is one of the mammalian homologues of bacterial DnaJ heat shock protein and regulates cellular processes by aiding in protein folding, transport, and assembly. Hsp40 protein contains the J-domain which controls interactions with the ATPase domain of DnaK. Function Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and rPubMed:24318877, PubMed:9499401}. References & CitationsTechnical ProtocolsCertificate of Analysis |
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