Sterile-filtered colorless solution (1mg/ml) in 20mM Tris-HCl, pH 7.4 and 100mM NaCl.
State of Matter
Liquid
Storage and Handling
Store at 4°C if entire vial will be used within 2-4 weeks of receipt. Store at or below -20°C for longer periods of time. Addition of a carrier protein (such as 0.1% HSA or BSA) is recommended for long term-storage.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Description
Description
Specificity
Recombinant Human Hsp90 alpha
Background
Hsp90, a mammalian heat shock protein, is a molecular chaperone that helps to keep a target protein in a folding- competent state. It has been found in cell cytosol, nucleus, and endoplasmic reticulum of many different tissues. Hsp90 functions as a dimer. It has an ATP-binding site and low ATPase activity. Its chaperone activity is enhanced at high temperatures, and its function is sensitive to bivalent cation concentrations.