IL-31 (Intermediate Domain) Blocking Peptide

IL-31 (Intermediate Domain) Blocking Peptide

Product No.: I-514

[product_table name="All Top" skus="I-514"]

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Target
Interleukin-31
Product Type
Blocking Peptide

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Antibody Details

Product Details

Reactive Species
Human
Product Concentration
0.2 mg/ml
Amino Acid Location
18 amino acids near the center of human IL31.
Formulation
This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Storage and Handling
Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Amino Acid Sequence
18 amino acids near the center of human IL31.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Background
Interleukin-31 (IL-31) is a T-cell cytokine, which is preferentially produced by type 2 helper T cells. The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A and oncostatin M receptor subunits. IL-31 is believed to play a role in inflammation of the skin.1 IL-31 represents a novel target for antipruritic drug development.2

Antigen Details

References & Citations

1. Stacey R Dillon et al.(2004) Nature Immunol. 5: 752 2. Homey B. et al.(2006) J Allergy Clin Immunol. 117: 411
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.