Recombinant Mouse IL-31

Recombinant Mouse IL-31

Product No.: I-418

[product_table name="All Top" skus="I-418"]

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Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Mouse

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Product Size
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Background

Interleukin-31 (IL-31) is a T-cell cytokine, which is preferentially produced by type 2 helper T cells. The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A and oncostatin M receptor subunits. IL-31 is believed to play a role in inflammation of the skin.1 IL-31 represents a novel target for antipruritic drug development.2

Protein Details

Purity
>95% by SDS-PAGE and HPLC
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
Data not yet available.
Protein Accession No.
Amino Acid Sequence
MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse IL-31 is Mr 15.8 kDa.
Predicted Molecular Mass
15.8
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient

References & Citations

1. Stacey R Dillon et al.(2004) Nature Immunol. 5: 752 2. Homey B. et al.(2006) J Allergy Clin Immunol. 117: 411
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.