Recombinant Human Galectin-3
Recombinant Human Galectin-3
Product No.: G-589
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Alternate Names LGALS3, Galactose-Specific Soluble Lectin 3, Lectin Galactoside-Binding Soluble 3, IgE-Binding Protein, MAC2, L-29, CBP35 Product Type Recombinant Protein Expression Host E. coli Cells Species Human |
Data
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BackgroundGalectin-3 is a beta-galactoside-binding protein that regulates many biologic processes, including cell adhesion, migration, cell growth, tumor progression, metastasis, and apoptosis.1 It is secreted from activated macrophages, basophils, and mast cells.2 Galectin-3 may play an important role in the acute phase of human atopic dermatitis. Protein DetailsPurity >90% by SDS-PAGE and analyzed by silver stain. Endotoxin Level <0.01 EU/µg as determined bythe LAL method Biological Activity The biological activity of Human Gal-3 was determined by its ability to agglutinate human red blood cells.<sup>2</sup> ED<sub>50</sub> is 3 - 10 μg/ml. Protein Accession No. Q6IBA7 Amino Acid Sequence Ala 2 - Ile 250 (Accession # Q6IBA7) N-terminal Sequence Analysis Ala2 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Human Galectin-3 is Mr 26 kDa. Predicted Molecular Mass 26 Formulation This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS), 4 mM β-mercaptoethanol (βME) containing 50 µg of BSA per 1 µg of cytokine. Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Eisenthal, A. et al. (2009) Pathol Res Pract. 2. Dahlgren, C. et al. (1998) Blood 91: 3430 2. Hadari, YR. et al. (2000) J. Cell Sci. 113:2385. IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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G716 | |
G590 | |
G-589 | |
G591 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
