Recombinant Mouse CCL1
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BackgroundChemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines.1 CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8.2 CCL1 may play a role in lymphocyte recruitment in bronchial asthma.3 Protein DetailsPurity >95% by SDS-PAGE and analyzed by silver stain. Endotoxin Level <0.01 EU/µg as determined by the LAL method Protein Accession No. Amino Acid Sequence ksmltvsnsc clntlkkelp lkfiqcyrkm gsscpdppav vfrlnkgres castnktwvq nhlkkvnpc N-terminal Sequence Analysis Lys24 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Mouse CCL1 is Mr 7.8 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 13-16 kDa. Predicted Molecular Mass 7.8 Formulation This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA). Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Krangel, MS. et al. (1992) Proceedings of the National Acad of Sci. 89: 2950 2. Roos, RS. et al. (1997) J Biol Chem. 272: 17251 3. Teran, LM et al. (2006) Eur Respir J. 28: 59 Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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