Anti-Mouse CCL1 (Clone 148107)
Pricing & Details
Purified Recombinant Mouse CCL1 (>98%)
<0.1 EU/µg as determined by the LAL method
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Storage and Handling
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Country of Origin
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
Other Applications Reported In Literature ?
Neutralization: This antibody is useful for neutralization of Mouse TCA-3 bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Mouse TCA-3 (at 10 ng/ml) is 0.6 - 3.0 µg/ml.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Rat Anti-Mouse Chemokine (C-C Motif) Ligand 1 (CCL1) (Clone 148107) recognizes an epitope on Mouse CCL1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines.1 CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8.2 CCL1 may play a role in lymphocyte recruitment in bronchial asthma.3
NCBI Gene Bank ID
References & Citations
1. Krangel, MS. et al. (1992) Proceedings of the National Acad of Sci. 89: 2950
2. Roos, RS. et al. (1997) J Biol Chem. 272: 17251
3. Teran, LM et al. (2006) Eur Respir J. 28: 59
Products are for research use only. Not for use in diagnostic or therapeutic procedures.