Recombinant Mouse Ephrin-A2
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BackgroundEphrin-A2 (EPHA2), also known as EFNA2 is an oncoprotein1 that is a member of the ephrin ligand family, which binds members of the Eph receptor family. Ephrin-A2 is a negative regulator of proliferation.2 EPHA2 plays a vital role in maintaining lens transparency.3 It also represents a new marker and novel target for the development of molecular therapeutics against glioblastoma multiforme (GBM).4 Protein DetailsPurity >90% by SDS Page and analyzed by silver stain. Endotoxin Level <0.1 EU/µg as determined by the LAL method Protein Accession No. N-terminal Sequence Analysis Glu23 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Mouse Ephrin-A2 is Mr 46 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 57 kDa. Predicted Molecular Mass 46 Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Xie, D. et al. (2007) Int J Oncol. 30: 865 2. Frisén, J. et al. (2005) Genes Dev. 19: 462 3. Hejtmancik, JF. et al. (2008) Mol Vis. 14: 2042 4. Debinski, W. et al. (2005) Mol Cancer Res. 3: 541 Certificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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