Anti-Mouse Ephrin-A2 – Biotin

NS0-Derived Recombinant Mouse Ephrin-A2 Extracellular Domain (Accession # P52801)

This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present.

Lyophilized

The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Next Day Ambient

Goat Anti-Mouse Ephrin-A2 recognizes Mouse Ephrin-A2. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

Ephrin-A2 (EPHA2), also known as EFNA2 is an oncoprotein¹ that is a member of the ephrin ligand family, which binds members of the Eph receptor family. Ephrin-A2 is a negative regulator of proliferation.² EPHA2 plays a vital role in maintaining lens transparency.³ It also represents a new marker and novel target for the development of molecular therapeutics against glioblastoma multiforme (GBM).⁴

1. Xie, D et al. (2007) Int J Oncol. 30: 865
2. Frisén, J. et al. (2005) Genes Dev. 19: 462
3. Hejtmancik, JF. et al. (2008) Mol Vis. 14: 2042
4. Debinski, W. et al. (2005) Mol Cancer Res. 3: 541