Recombinant Mouse IL-9

Recombinant Mouse IL-9

Product No.: I-380

[product_table name="All Top" skus="I-380"]

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Alternate Names
Interleukin-9, Cytokine, T-Cell Growth Factor P40, HP40, P40
Product Type
Recombinant Protein
Expression Host
sf Insect Cells
Species
Mouse

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Select Product Size
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Background

Interleukin 9, also known as IL9, is a TH2 cytokine1 belonging to the group of interleukins. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. IL-9 stimulates the proliferation of a variety of hematopoietic lineages through its interaction with a receptor of the cytokine receptor superfamily.2 IL-9 plays a role in the complex pathogenesis of bronchial hyperresponsiveness as a risk factor for asthma.3

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
Measured in a cell proliferation assay using TS1 mouse helper T cells.<sup>4</sup> The ED<sub>50</sub> for this effect is 0.01‑0.03 ng/mL.
Protein Accession No.
Amino Acid Sequence
qrcsttwgir dtnylienlk ddppskcscs gnvtsclcls vptddcttpc yregllqltn atqksrllpv fhrvkrivev lknitcpsfs cekpcnqtma gntlsflksl lgtfqktemq rqksrp
N-terminal Sequence Analysis
Gln19 is predicted
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse IL-9 is Mr 14.2 kDa. However, multiple bands were observed by migration on SDS-PAGE with an actual molecular weight between 16-25 kDa (reducing conditions).
Predicted Molecular Mass
14.2
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Renauld, JC. et al. (1995) J. Immunol 154: 5061
2. Yang, YC. et al. (1995) J. Biol. Chem. 270: 20497
3. Levitt, RC. et al. (1997) Proc Natl Acad Sci USA. 94: 13175
4. Uyttenhove, C. et al. (1988) Proc. Natl. Acad. Sci. 85:6934

Certificate of Analysis

IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.