Recombinant Mouse IL-9

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Pricing & Details

Product. No.I-380
Alternate Names
Interleukin-9, Cytokine, T-Cell Growth Factor P40, HP40, P40
Expression Host
Sf 21 Insect Cells
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
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I-380-10 µg
10 µg
$359.00
In stock
Max:
Min: 1
Step: 1
I-380-50 µg
50 µg
$969.00
In stock
Max:
Min: 1
Step: 1

Background

Interleukin 9, also known as IL9, is a TH2 cytokine1 belonging to the group of interleukins. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. IL-9 stimulates the proliferation of a variety of hematopoietic lineages through its interaction with a receptor of the cytokine receptor superfamily.2 IL-9 plays a role in the complex pathogenesis of bronchial hyperresponsiveness as a risk factor for asthma.3

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
Measured in a cell proliferation assay using TS1 mouse helper T cells.4 The ED50 for this effect is 0.01‑0.03 ng/mL.
Expression Host
Sf 21 Insect Cells
Protein Accession No.
Amino Acid Sequence
qrcsttwgir dtnylienlk ddppskcscs gnvtsclcls vptddcttpc yregllqltn atqksrllpv fhrvkrivev lknitcpsfs cekpcnqtma gntlsflksl lgtfqktemq rqksrp
N-terminal Sequence Analysis
Gln19 is predicted
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse IL-9 is Mr 14.2 kDa. However, multiple bands were observed by migration on SDS-PAGE with an actual molecular weight between 16-25 kDa (reducing conditions).
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Renauld, JC. et al. (1995) J. Immunol 154: 5061
2. Yang, YC. et al. (1995) J. Biol. Chem. 270: 20497
3. Levitt, RC. et al. (1997) Proc Natl Acad Sci USA. 94: 13175
4. Uyttenhove, C. et al. (1988) Proc. Natl. Acad. Sci. 85:6934
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.