Recombinant Mouse IP-10 (CXCL10)

Home/Recombinant Proteins/Recombinant Mouse IP-10 (CXCL10)

Pricing & Details

Product. No.I-229
Alternate Names
IP-10, C7, IFI10, INP10
Expression Host
E. coli
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-229-10 µg
10 µg
$269.00
In stock
Max:
Min: 1
Step: 1
I-229-50 µg
50 µg
$500.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Background

Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family. CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts.1 CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.2,3 CXCL10 plays a role in the regulation of tubular cell proliferation following renal ischemia-reperfusion injury.4

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.01 EU/µg as determined by the LAL method
Biological Activity
Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR3. The ED50 for this effect is 0.05-0.3 µg/mL.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
miplartvrc ncihiddgpv rmraigklei ipaslscprv eiiatmkknd eqrclnpesk tiknlmkafs qkrskrap
N-terminal Sequence Analysis
Met
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse CXCL10 is Mr 8.8 kDa.
Formulation
This recombinant protein was 0.2 μm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (IX PBS) pH 7.2 - 7.4 with no calcium, magnesium, or preservatives present.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Luster, AD. et al.(1985) Nature 315: 672
2. Dufour, JH. et al.(2002) J. Immunol. 168
3. Angiolillo, AL. et al.(1995) J. Exp. Med. 182: 155
4. Kaneko, S. et al.(2008) Nephron Exp. Nephrol. 109:(1):c29-38
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok