Recombinant Mouse SDF-1α

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Pricing & Details

Product. No.S501
Alternate Names
Stromal Cell-Derived Factor-1α, CXCL12, TLSF-a, Pre-B Cell Growth Stimulating Factor (PBSF)
Expression Host
E. coli
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
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S501-10 µg
10 µg
$249.00
In stock
Max:
Min: 1
Step: 1
S501-50 µg
50 µg
$500.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Background

SDF-1alpha (stromal cell-derived factor-1 alpha) is an alpha-chemokine for haematopoietic stem cells (HSC).1 SDF-1 alpha plays a role in two important processes of granule cell maturation - proliferation and migration - assisting in the achievement of appropriate cell number and position in the cerebellar cortex.2 SDF-1 alpha is also involved in the trafficking of hematopoietic progenitors and stem cells.3 It is expressed by liver cells and in liver diseases.4

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.01 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Mouse SDF-1α was determined by its ability to chemoattract cultured human lymphocytes, and mouse BaF/3 cells transfected with human CXCR4. The expected ED50 for this effect is typically 3-9 ng/ml, and 0.15-0.6 ng/ml, respectively.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
kpvslsyrc pcrffeshia ranvkhlkil ntpncalqiv arlknnnrqv cidpklkwiq eylekalnk
N-terminal Sequence Analysis
Lys22
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse SDF-1α is Mr 8 kDa.
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient

References & Citations

1. Ratajczak, MZ. et al. (2003) Folia Histochem Cytobiol. 41: 13
2. Luster, AD. et al. (2001) Development 128: 1971
3. Vannier, JP. et al. (2002) Eur Cytokine Netw 12: 223
4. Dickenson, J. et al. (2008) Iran J Allergy Asthma Immunol. 7: 61
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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