Recombinant Rat IL-17

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Pricing & Details

Product. No.I-812
Alternate Names
CTLA8, IL17A
Expression Host
E. coli
Species
Rat
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-812-25 µg
25 µg
$224.00
In stock
Max:
Min: 1
Step: 1
I-812-100 µg
100 µg
$545.00
In stock
Max:
Min: 1
Step: 1
I-812-500 µg
500 µg
$2,737.00
In stock
Max:
Min: 1
Step: 1
I-812-1 mg
1 mg
$3,456.00
In stock
Max:
Min: 1
Step: 1

Background

Interleukin 17 (IL-17) is a T cell cytokine that induces monocyte migration and inflammation.1 IL-17-producing cell could serve as a potential prognostic marker and a novel therapeutic target for hepatocellular carcinoma (HCC).2 IL-17 may be important in recruiting monocytes into the joints of patients with RA, supporting IL-17 as a therapeutic target in RA.1

Protein Details

Purity
<95% by SDS Page
Biological Activity
Recombinant Rat IL-17A is fully biologically active when compared to standards via dose-dependent induction of IL-6 production in cultured rat fibroblasts.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Rat IL-17A is Mr 30.0 kDa.
Formulation
The protein was 0.2 µm filtered and lyopohilized from 10 mM NaCitrate, pH 3.0
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Pope, RM. et al. (2009) J Immunol. 182: 3884
2. Zheng, L. et al. (2009) J Hepatol. 50(5):980-989.
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
I-198
I-812
Products are for research use only. Not for use in diagnostic or therapeutic procedures.