Anti-Dengue, NS1 (DENV-7846)

Anti-Dengue, NS1 (DENV-7846)

Product No.: D220

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Clone
DENV-7846
Target
NS1
Formats AvailableView All
Product Type
Hybridoma Monoclonal Antibody
Isotype
Mouse IgG1
Applications
ELISA
,
IF

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Select Product Size
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Antibody Details

Product Details

Reactivity Species
Dengue Virus
Host Species
Mouse
Product Concentration
≥1.0 mg/ml
Purity
≥90%
Formulation
Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
State of Matter
Liquid
Product Preparation
This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
2-8°C Wet Ice
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA: 1:20-1:200,
IF: 1:10-1:50
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Anti-Dengue virus (Clone DENV-7846) is specific for NS1 of all four serotypes of Dengue virus.
Matched Pair
Best pair (capture/detection), DENV-7846/DENV-1679
Background
Dengue virus (DENV) is the most common insect-transmitted virus to target humans, with an estimated 390 million infections annually1. DENVs are members of the Flaviviridae family (single-stranded, positive-sense RNA viruses) and can be divided into four closely related but antigenically distinct serotypes2. Encoded in the genome is NS1 (Non-Structural Protein 1) which plays a critical role in the viral life cycle and interacts with the host immune system. NS1 is present in the serum of infected individuals and can be detected early during acute infection, making it a valuable diagnostic marker for dengue fever.

Antigen Details

Research Area
Category A Pathogens
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Infectious Disease
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Matched Pair
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Viral
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IVD Raw Material

References & Citations

1. Smith SA, de Alwis AR, Kose N, et al. mBio. 4(6):e00873-13. 2013.
2. Lecouturier V, Berry C, Saulnier A, et al. Vaccine. 37(32):4601-4609. 2019.
Indirect Elisa Protocol
IF

Formats Available

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Prod No.
Description
D220
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.