Anti-Epidiymis Protein 4 (HE4) Antibody (34085)

Anti-Epidiymis Protein 4 (HE4) Antibody (34085)

Product No.: 34085

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Clone
3C24
Target
Epidiymis Protein 4 (HE4)
Formats AvailableView All
Product Type
Monoclonal
Alternate Names
Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5
Isotype
Mouse IgG1
Applications
ELISA

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Native human epididymis protein 4 (HE4)
Product Concentration
Lot Specific
Formulation
PBS, pH 7.2, 0.09% sodium azide.
State of Matter
Liquid
Product Preparation
Purified by Protein G affinity chromatography
Storage and Handling
Store product at 4°C.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA: for sandwich ELISA use #34085 as capture antibody and #34084 or #34086 as detection antibody.

End users should determine optimal antibody concentrations relative to their samples.
Additional Applications Reported In Literature ?
ELISA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
These antibodies recognize HE4. The epitope recognized by #34085 is different from the epitope recognized by #34084 and #34086.
Background
Human epididymis protein 4 (HE4) is primarily expressed in the reproductive and respiratory tracts and is overexpressed in epithelial ovarian cancer. The HE4 gene product is an Nglycosylated protein which is secreted into the extracellular environment and can be detected in the bloodstream of patients with ovarian cancer. HE4 was found to be elevated in more than half of ovarian tumors that do not express CA125.
Function
Broad range protease inhibitor. {PubMed:23139753}.
NCBI Gene Bank ID
UniProt.org
Research Area
Cancer Research

References & Citations

Indirect Elisa Protocol

Certificate of Analysis

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.