Anti-FBG3 Antibody (28104)
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Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Immunogen Synthetic peptide corresponding to amino acids 103-119 (EWKVEDLSRDQRKEFPN) of human Product Concentration Lot Specific Formulation PBS, pH 7.4. State of Matter Liquid Product Preparation Purified by peptide immuno-affinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting : use at 1:500 dilution. A band of approximately 31 kDa is detected.
Positive control: recombinant human FBG3. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rabbit Polyclonal Antibody specific to FBG3 (F Box 3) Background F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F- box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues. Function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. NCBI Gene Bank ID UniProt.org Research Area Neuroscience References & CitationsIlyin,GP et al. (2002) Gene 296:11-20. Technical Protocols  Certificate of Analysis |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
