Anti-Herpes Simplex Virus, gD (HSV-0846)

Anti-Herpes Simplex Virus, gD (HSV-0846)

Product No.: H280

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Clone
HSV-0846
Target
Glycoprotein D, gD
Formats AvailableView All
Product Type
Hybridoma Monoclonal Antibody
Alternate Names
HSV, HSV-1, HSV-2
Isotype
Mouse IgG1
Applications
ELISA
,
IF
,
Lateral Flow

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Antibody Details

Product Details

Reactivity Species
Herpes Simplex Virus 1 and 2
Host Species
Mouse
Product Concentration
≥1.0 mg/ml
Purity
≥90%
Formulation
Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
State of Matter
Liquid
Product Preparation
This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
2-8°C Wet Ice
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA: 1:20-1:200,
Lateral Flow,
IF: 1:10-1:50
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Anti-HSV (Clone HSV-0846) has known reactivity for glycoprotein D (gD) of HSV 1 & 2.
Matched Pair
Best ELISA pair (capture/conjugate), HSV-0846/HSV-7315.
Background
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are two closely related enveloped DNA viruses that are members of the Herpesviridae family of viruses. HSV is a neurotropic virus that initially infects and replicates in epithelial cells of the mucosal epithelium before it establishes lifelong latent infection within sensory neurons. While both viruses can cause genital infection, HSV-2 is most often the cause of these infections. HSV-1 is typically spread during childhood and has a global prevalence of about 90%. Both viruses can be spread to other tissues via contact with infected skin or mucous membranes. Glycoprotein D (gD) is the major receptor binding protein of HSV and binds to at least one of the three known entry receptors: herpesvirus entry mediator (HVEM), nectin-1, and 3-O sulfated heparan sulfate.

Antigen Details

Antigen
Glycoprotein D, gD
Research Area
Infectious Disease
.
Matched Pair
.
Sexually Transmitted Infections
.
Viral
.
IVD Raw Material
Indirect Elisa Protocol
IF
Lateral Flow

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.