Anti-Human beta-Actin (CT)

Anti-Human beta-Actin (CT)

Product No.: B516

[product_table name="All Top" skus="B516"]

- -
- -
Target
beta-Actin
Product Type
Polyclonal Antibody
Applications
ICC
,
IP
,
WB

- -
- -
Product Size

Data

- -
- -

Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:B502
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human β-Actin recognizes an epitope near the C-terminus of human, mouse and rat β-Actin. This polyclonal antibody was purified using affinity chromatography.
Background
Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism (reviewed in 1). The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging (2). β-actin is one of six different actin isoforms which have been identified. Like GAPDH, β-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.

Antigen Details

References & Citations

1. Lambrechts, A. et al. (2004) Int. J. Biochem. Cell Biol. 36:1890
2. Gourlay, CW. et al. (2005) Nat. Rev. 6:583
ICC
Immunoprecipitation Protocol
General Western Blot Protocol
- -
- -
Prod No.
Description
B516
Products are for research use only. Not for use in diagnostic or therapeutic procedures.