Anti-Human CD28 – Purified (CODEX® Ready)

Pricing & Details

Product No.C511
Clone
CD28.2
Protein
CD28
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
MGC138290, Tp44
Isotype
Mouse
IgG1 κ
Applications
CODEX®
,
IHC FF
Prod No.
Size
Price
Avail.
Qty
Add to cart
C511-50µg
50 µg
$95.00
In stock
Max:
Min: 1
Step: 1

CODEX® Details

Validation Notes
Clone CD28.2 has been validated for use on CODEX® using human tonsil Fresh Frozen (FF) tissue.
Tissue Screened
Tonsil
Tissue Preparation
FF (Fresh Frozen)

Antibody and Reporter Details

Reactivity Species
Human
Host Species
Mouse
Concentration
≥ 2.0 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Storage and Handling
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications and Recommended Usage?
Quality Tested by Leinco
CODEX® This CD28 (Clone CD28.2) antibody is formulated to simplify the antibody preparation needed when performing a CODEX® barcode conjugate. The suggested concentration is 0.5 mg/ml.
RRID
AB_2893568
Country of Origin
USA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone CD28.2 recognizes an epitope on human CD28.
Antigen Distribution
CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
Background
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.

Antigen Details

Protein
Ligand/Receptor
CD80, CD86
PubMed
NCBI Gene Bank ID

References & Citations

1. Stern, LJ. et al. (2005) Proc Natl Acad Sci U S A.102(10):3744-9 PubMed
IHC

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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