Anti-Human Cytokeratin 6/18 – Purified

Anti-Human Cytokeratin 6/18 – Purified

Product No.: C161

[product_table name="All Top" skus="C161"]

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Clone
LP34
Target
Cytokeratin 6/18
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
IgG1 κ
Applications
IHC FF
,
IHC FFPE

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Select Product Size
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
UnKnown
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Mouse Anti-Human Cytokeratin 18,6 (Clone LP34) recognizes Human Cytokeratin 18,6. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Anti-Human Cytokeratin 18, 6 (clone LP34) reacts with the cytokeratin polypeptides 18 and 6, with molecular weights of 45 kDa and 56 kDa, respectively. The antibody does not react with keratins 1, 8, or 19. Anti-Cytokeratin 18, 6 reacts in cryostat sections with epithelial tissues known to contain filamentous keratins. It reacts with single glandular epithelia to stratified squamous epithelia. Anti-Cytokeratin 18,6 may be used in research studies to identify tumors as being of epithelial or mesothelial origin enabling aplastic carcinomas to be distinguished from other non-carcinoma types of tumors.1,2 The antibody may also be used to trace areas of epithelial tissue in mixed tumors.

References & Citations

1. Moll, WR. et al. (1982) Cell 31:11
2. Gatter, KC. et al. (1982) J. Clin. Path. 35:125
IHC FF
IHC FFPE

Certificate of Analysis

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.