Anti-Human IL-15 Rα (Clone 151307)

Pricing & Details

Product No.I-626
Clone
151307
Protein
IL-15 R alpha
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Interleukin-15 Receptor Alpha, IL15RA, MGC104179
Isotype
Mouse
IgG1
Applications
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-626-25 µg
25 µg
$195.00
In stock
Max:
Min: 1
Step: 1
I-626-500 µg
500 µg
$525.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Host Species
Mouse
Immunogen
Purified Recombinant IL-15 Rα (Accession # EAW86418)
Formulation
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Storage and Handling
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Country of Origin
USA
Shipping
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
Western Blotting: To detect IL-15 Rα this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:M114 and a chromogenic substrate such as PN:T343. The detection limit for IL-15 Rα is 25 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. A suitable Western blotting control is PN:I-196.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti- Interleukin-15 Rα (IL-15 Rα) (Clone 151307) recognizes an epitope on IL-15 Rα. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody displays no cross-reactivity with rmIL-15 Rα, rhIL-2 Rα, rhIL-2 Rβ or rhIL-2 Rγ.
Background
Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor. IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. The receptors of IL15 and IL2 share two subunits, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. IL15RA is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2.

Antigen Details

General Western Blot Protocol

Formats Available

Prod No.
Description
I-626
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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