Anti-Human MIP-5

Purified Recombinant Human MIP-5 (>98%)

This antigen affinity purified polyclonal antibody is aseptically filtered and lyophilized from PBS with no carrier proteins or preservatives added.

0.5-2.0

The lyophilized antibody should be stored desiccated at -20°C. The reconstituted antibody can be stored for at least six weeks at 4°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Neutralization: Measured by its ability to neutralize CCL15/MIP‑1δ-induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CCR1. The Neutralization Dose (ND₅₀) is typically 0.5-2.5 µg/mL in the presence of 15 ng/mL Recombinant Human CCL15/MIP‑1δ 68 aa.

Goat Anti-Human Macrophage Inflammatory Protein-5 (MIP-5) recognizes Human MIP-5. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

Macrophage inflammatory protein-5 (MIP-5) is a CC chemokine is expressed at high levels in liver, intestine, and in lung leukocytes. It induces chemotaxis of monocytes, T-lymphocytes and eosinophils. MIP-5 competes with MIP-1-alpha for binding to CC-Chemokine receptor CCR1, and with MCP-3 for binding to CCR3.¹

1. Coulin, F. et al. (1997) J. Biochem. 248: 507