This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Rabbit Anti-Human Nerve Growth Factor Receptor (NGFR) recognizes Human NGFR. This polyclonal antibody was purified using affinity chromatography.
Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation.1 It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination.2 p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism.3
References & Citations
1. Ashworth, A. et al. (2006) Modern Path. 19: 307
2. Carter, BD. et al. (2004) Prog. Brain Res. 146: 25
3. Itano, T. et al. (2001) Acta Med Okayama 55: 19
Products are for research use only. Not for use in diagnostic or therapeutic procedures.