Anti-Human TL1-A (NT)

Pricing & Details

Product No.T306
Protein
TL1-A
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
TNF-Ligand-Related Molecule 1-A, TNFSF15, MGC129934, MGC129935, TL1, VEGI, VEGI192A
Applications
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
T306-20ug
20 µg
$195.00
In stock
Max:
Min: 1
Step: 1
T306-0.1 mg
0.1 mg
$397.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
PN:T328
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human TNF-Ligand-Related Molecule 1-A (TL1-A) recognizes Human TL1-A. This polyclonal antibody was purified using affinity chromatography.
Background
TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.1 TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.2

Antigen Details

Protein
PubMed

References & Citations

1. Wei, P. et al. (2003) J Biol Chem. 278: 39251
2. Cominelli, F. et al. (2006) PNAS 103: 8441
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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