Anti-Human TL1-A (NT)

Anti-Human TL1-A (NT)

Product No.: T306

[product_table name="All Top" skus="T306"]

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Target
TL1-A
Product Type
Polyclonal Antibody
Alternate Names
TNF-Ligand-Related Molecule 1-A, TNFSF15, MGC129934, MGC129935, TL1, VEGI, VEGI192A
Applications
WB

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Product Size
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:T328
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human TNF-Ligand-Related Molecule 1-A (TL1-A) recognizes Human TL1-A. This polyclonal antibody was purified using affinity chromatography.
Background
TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.1 TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.2

Antigen Details

PubMed

References & Citations

1. Wei, P. et al. (2003) J Biol Chem. 278: 39251
2. Cominelli, F. et al. (2006) PNAS 103: 8441
General Western Blot Protocol
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.