Anti-Human von Willebrand Factor Antibody

Anti-Human von Willebrand Factor Antibody

Product No.: 19818

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Clone
VW92-3
Target
Human von Willebrand Factor
Formats AvailableView All
Product Type
Monoclonal
Alternate Names
vWF [Cleaved into: von Willebrand antigen 2]
Isotype
IgG2a
Applications
IHC
,
WB

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Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
Human plasma von Willebrand Factor.
Formulation
PBS, 1% BSA, pH 7.4, lyophilized.
State of Matter
Lyophilized
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
The stock solution (2. 0mg/ml) can be stored in aliquots at - 20°C for 1 year or can be stored at 4°C for 6 months after adding 0.1% sodium azide. Dilutions of stock solution should not be stored.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA: 1-10ug/ml with vWF on the solid phase

Western Blot: 5-10ug/ml; useful under non-reducing conditions.

Immunohistochemistry: 5-10ug/ml on paraffin embedded and frozen tissue sections.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Monoclonal Antibody specific to von Willebrand Factor

Antigen Details

Function
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
NCBI Gene Bank ID
UniProt.org

References & Citations

IHC
General Western Blot Protocol

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.