Anti-Lead [Clone Pb1]
Anti-Lead [Clone Pb1]
Product No.: 60001
- -
- -
Clone Pb1 Target Lead Formats AvailableView All Product Type Monoclonal Isotype Mouse IgM Applications ELISA |
- -
- -
Antibody DetailsProduct DetailsReactive Species Lead Host Species Mouse Immunogen Lead conjugated to keyhole limpet hemocyanin (KLH) by proprietary chemistry. Product Concentration Lot Specific Formulation Whole antiserum State of Matter Liquid Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Indirect ELISA: optimized for lead-RSA (rabbit serum albumin) on solid phase at 200ng/well. Ascites diluted 1:100,000 produces an O.D. signal of 0.5.
Competition ELISA: with lead-RSA on the solid phase at 200ng/well, 50% inhibition of antibody binding is achieved with Pb2+ at 800ng/well. These are recommended concentrations. End users should determine optimal concentrations for their applications.Not all applications have been investigated. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Monoclonal Antibody specific to Lead Background Lead exposure remains a major public health issue, with many children in the United States showing detectable blood lead levels, especially in older housing with residual lead-based paint and contaminated environments. Chronic lead exposure is associated with neurotoxicity and impaired neurodevelopment, yet the cellular and molecular mechanisms of lead-induced damage to the central nervous system are still being defined. Leinco’s Anti-Lead [Clone Pb1] monoclonal antibody is designed for use in ELISA and related immunoassays to detect lead, supporting development of sensitive laboratory tests for lead exposure and research into the mechanisms of lead toxicity in environmental, clinical, and neuroscience studies. Research Area Neuroscience . Toxin References & Citations1.) Lin TJ and Chung MF 2008 Sensors 8: 582-593. Refers to product no. 60001. 2.) Sanders T, Liu Y, Buchner V, Tchounwou PB. Neurotoxic effects and biomarkers of lead exposure: a review. Rev Environ Health. 2009 Jan-Mar;24(1):15-45. doi: 10.1515/reveh.2009.24.1.15. PMID: 19476290; PMCID: PMC2858639. Technical Protocols Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
