Anti-Morphine-6 [Clone MOR101]

Morphine conjugated at the C6 position to bovine serum albumin.

This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added.

Liquid

Produced in vitro via hybridoma cell culture and purified using Protein A/G affinity chromatography. The purified immunoglobulin is dialyzed against sterile phosphate-buffered saline (PBS), 0.2 µm filtered, and supplied free of stabilizing carrier proteins.

Country of Origin: Manufactured, purified, and packaged in the United States of America (St. Louis, MO) by Leinco Technologies under an ISO 9001 / ISO 13485 certified Quality Management System. Certified free of transmissible spongiform encephalopathy (TSE) and bovine spongiform encephalopathy (BSE) risk agents.

This antibody is stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Next Day 2-8°C

This antibody has a Kd of 2 nM for morphine and related alkaloids (e.g., codeine, nalorphine, and naltrexone).

Morphine is a highly potent opiate analgesic that is heavily monitored in clinical toxicology, pain management, and drugs of abuse (DOA) testing. In the body, morphine is primarily metabolized by the liver into morphine-3-glucuronide (M3G) and the highly active metabolite morphine-6-glucuronide (M6G). Because M6G and free morphine are readily excreted in urine, detecting these target conjugates is essential for accurate opiate consumption screening.

The Anti-Morphine-6 Monoclonal Antibody (Clone MOR101) is a high-affinity reagent specifically engineered to recognize morphine and its structurally related conjugates at the 6-position. Validated for competitive Enzyme-Linked Immunosorbent Assays (ELISA), Clone MOR101 serves as a critical raw material for in vitro diagnostic (IVD) assay developers. Its high specificity ensures low cross-reactivity with non-target pharmaceuticals, allowing manufacturers to build robust, highly sensitive rapid point-of-care tests (POCT) and laboratory-based immunoassays for opiate detection.

1. Murphy PB, Bechmann S, Barrett MJ. Morphine. StatPearls. Treasure Island (FL): StatPearls Publishing; 2024.