Anti-Mouse CD200 (Clone OX-90) – Purified in vivo GOLD™ Functional Grade

Pricing & Details

Product No.C857
Clone
OX-90
Protein
CD200
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
OX-2
Isotype
Rat
IgG2a κ
Applications
FC
,
IHC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C857-1.0mg
1.0 mg
$105.00
In stock
Max:
Min: 1
Step: 1
C857-5.0mg
5.0 mg
$355.00
In stock
Max:
Min: 1
Step: 1
C857-25mg
25 mg
$965.00
In stock
Max:
Min: 1
Step: 1
C857-50mg
50 mg
$1,595.00
In stock
Max:
Min: 1
Step: 1
C857-100mg
100 mg
$2,300.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Rat
Product Concentration
≥ 5.0 mg/ml
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Purity
≥95% monomer by analytical SEC
>95% by SDS Page
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Product Preparation
Functional grade preclinical antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Other Applications Reported In Literature ?
FC
IHC
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone OX-90 reacts with murine CD200 (OX-2).
Antigen Distribution
Thymocytes, neurons, B cells, splenic follicular dendritic cells and endothelium, and subsets of T cells and dendritic cells
Background
CD200 (OX-2) is an immune suppressor that regulates the of induction of cytokine production by conventional allostimulatory DC1,2. CD200 limits pro-inflammatory signals and has been shown to play an important role in cancer and immune disorders3,4.

Antigen Details

Protein
PubMed
Research Area
Immunology

References & Citations

1. Gorczynski L, Chen Z, Hu J, et. al. J Immunol. Jan 15;162(2):774-81. 1999.
2. Koning N, Swaab DF, Hoek RM, Huitinga I. J Neuropathol Exp Neurol. Feb;68(2):159-67. 2009.
3. Stanley H. Appel, David R. Beers, Weihua Zhao. Neurobiology of Brain Disorders.
4. Liu JQ, Hu A, Zhu J, et. al. Adv Exp Med Biol. 1223:155-165. 2020.
Flow Cytometry
IHC

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.