Anti-Mouse IL-1α – Purified In vivo GOLD™ Functional Grade

Pricing & Details

  
Clone
ALF-161
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Isotype
Armenian Hamster
IgG1
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-428-1.0 mg
1.0 mg
$95.00
In stock
I-428-5.0 mg
5.0 mg
$298.00
In stock
I-428-25 mg
25 mg
$775.00
In stock
I-428-50 mg
50 mg
$1,275.00
In stock
I-428-100 mg
100 mg
$1,998.00
In stock
  

Antibody Details

Reactivity Species
Mouse
Host Species
Armenian Hamster
Product Concentration
1.0 mg/ml
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Product Preparation
Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Additional Reported Applications For Relevant Conjugates
N
For specific conjugates of this clone, review literature for suggested application details.

Description

Specificity
Anti-Mouse IL-1α recognizes Mouse IL-1α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.

Antigen Details

Protein Family
Interleukin-1 Alpha
NCBI Gene Bank ID
General Western Blot Protocol
  

Formats Available

  
Products are for research use only. Not for use in diagnostic or therapeutic procedures.