Anti-Mouse Vγ 3 (TCR) – APC
Anti-Mouse Vγ 3 (TCR) – APC
Product No.: T144
- -
- -
Clone 536 Target Vγ 3 T-Cell Receptor Formats AvailableView All Product Type Monoclonal Antibody Isotype IgG |
- -
- -
Antibody DetailsProduct DetailsReactive Species Mouse Host Species Syrian Hamster Product Concentration 0.2 mg/ml Formulation This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This APC conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C Excitation Laser Red Laser (650 nm) RRIDAB_2894347 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Anti-Mouse Vγ 3 TCR antibody recognizes an epitope of the variable region (Vγ 3) gene product. Antibody from clone 536 immunoprecipitates the TCR heterodimer with two subunits of apparent molecular mass of 52 and 42 kDa. Background The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. Antigen Distribution The antibody 536 stained less than 1% of cells in adult thymus (AKR), splenocytes, lymph node, adult CD4-8- thymocytes, and adult CD4-8-, T splenocyte. 92% of day 14 old BALB/C fetal thymus, 86% of C57BL/6 dEC (Thy-1+) and 94% of AKR dEC (Thy-1+) stained positive using this antibody. PubMed Research Area Adaptive Immunity . Immunology References & CitationsHavran, et al. (1989) Pro. Natl. Acad. Sci. USA 86:4185 |
Formats Available
- -
- -
Prod No. | Description |
---|---|
T574 | |
T566 | |
T567 | |
T568 | |
T570 | |
T571 | |
T572 | |
T133 | |
T136 | |
T144 | |
T135 | |
T134 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.