Anti-Osteonectin/SPARC Antibody (58008)
Anti-Osteonectin/SPARC Antibody (58008)
Product No.: 58008
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Clone ON1-1 Target Osteonectin/SPARC Formats AvailableView All Product Type Monoclonal Alternate Names Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine Isotype IgG1 Applications FACS , IHC , WB |
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Antibody DetailsProduct DetailsReactivity Species Bovine ⋅ Human ⋅ Porcine ⋅ Rabbit Host Species Mouse Immunogen Bovine bone osteonectin (SPARC) Formulation 10 mM PBS, pH 7.4, 1% BSA, lyophilized State of Matter Lyophilized Product Preparation Purified by immunoaffinity chromatography Storage and Handling This product does not contain preservative. Lyophilized antibody is stable at 4°C for 2 years. Store the reconstituted solution (2. 0mg/ml) in aliquots at -20°C for one year or at 4°C for 6 months after adding 0.1% sodium azide. Dilutions of stock solution should not be stored. Avoid repeated freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1-10ug/ml with immobilized antigen
Western Blot: 1-10ug/ml, reducing and non-reducing conditions. Immunohistochemistry: 1-10ug/ml, paraffin-embedded and frozen tissue sections. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Monoclonal Antibody specific to human,
bovine, rabbit, and porcine bone-derived
and platelet derived Osteonectin (SPARC) as well
as with thrombin-stimulated platelets. Antigen DetailsFunction Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity. NCBI Gene Bank ID UniProt.org Research Area Cell Adhesion References & CitationsTechnical ProtocolsFACS   |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
