Anti-Rotavirus (ROTA-3868)

Anti-Rotavirus (ROTA-3868)

Product No.: R172

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Clone
ROTA-3868
Target
Rotavirus
Formats AvailableView All
Product Type
Hybridoma Monoclonal Antibody
Isotype
Mouse IgG2b
Applications
ELISA
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Lateral Flow

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Select Product Size
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Antibody Details

Product Details

Reactivity Species
Rotavirus
Host Species
Mouse
Product Concentration
≥1.0 mg/ml
Purity
≥90%
Formulation
Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
State of Matter
Liquid
Product Preparation
This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
2-8°C Wet Ice
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA: 1:20-1:200
Additional Applications Reported In Literature ?
Lateral Flow
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Anti-Rotavirus (Clone ROTA-3868) is specific for the intact virus of strains RRV, WA, SA11 and bovine. It is non-reactive with Influenza A and B, Adenovirus, M. pneumoniae, H. pylori, Parainfluenza Virus 1, 2, 3, and mammalian cells.
Matched Pair
Best ELISA pair (capture/detection), ROTA-3868/ROTA-2740
Background
Rotavirus is a highly contagious, double-stranded RNA virus that is the leading cause of severe gastroenteritis in infants and young children worldwide. It belongs to the Reoviridae family and is classified into different serotypes based on the antigenic properties of its outer protein coat. Rotavirus spreads primarily through the fecal-oral route, either by direct contact with an infected person or by consuming contaminated food or water. The virus replicates in the small intestine, leading to the destruction of the intestinal epithelial cells, which results in diarrhea, vomiting, fever, and dehydration. Rotavirus infections are particularly dangerous in developing countries with limited access to proper sanitation and healthcare, where they contribute significantly to childhood morbidity and mortality. Vaccination against rotavirus has shown to be highly effective in reducing severe rotavirus infections and associated hospitalizations.

Antigen Details

Research Area
Infectious Disease
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Matched Pair
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Viral
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IVD Raw Material

References & Citations

1. Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases. Link
Indirect Elisa Protocol
Lateral Flow

Formats Available

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Prod No.
Description
R172
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.