Anti-Rotavirus (ROTA-3868)
Anti-Rotavirus (ROTA-3868)
Product No.: R172
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Clone ROTA-3868 Target Rotavirus Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Isotype Mouse IgG2b Applications ELISA , Lateral Flow |
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Antibody DetailsProduct DetailsReactivity Species Rotavirus Host Species Mouse Product Concentration ≥1.0 mg/ml Purity ≥90% Formulation Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1:20-1:200 Additional Applications Reported In Literature ? Lateral Flow Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Rotavirus (Clone ROTA-3868) is specific for the intact virus of strains RRV, WA, SA11 and bovine. It is non-reactive with Influenza A and B, Adenovirus, M. pneumoniae, H. pylori, Parainfluenza Virus 1, 2, 3, and mammalian cells. Matched Pair Best ELISA pair (capture/detection), ROTA-3868/ROTA-2740 Background Rotavirus is a highly contagious, double-stranded RNA virus that is the leading cause of severe gastroenteritis in infants and young children worldwide. It belongs to the Reoviridae family and is classified into different serotypes based on the antigenic properties of its outer protein coat. Rotavirus spreads primarily through the fecal-oral route, either by direct contact with an infected person or by consuming contaminated food or water. The virus replicates in the small intestine, leading to the destruction of the intestinal epithelial cells, which results in diarrhea, vomiting, fever, and dehydration. Rotavirus infections are particularly dangerous in developing countries with limited access to proper sanitation and healthcare, where they contribute significantly to childhood morbidity and mortality. Vaccination against rotavirus has shown to be highly effective in reducing severe rotavirus infections and associated hospitalizations. Antigen DetailsResearch Area Infectious Disease . Matched Pair . Viral . IVD Raw Material References & Citations1. Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases. Link Technical Protocols |
Formats Available
