Anti-Streptococci Group A Antibody (15504)

UV-inactivated Strep. pyogenes cells

This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added.

Liquid

Antibodies are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles.

Next Day 2-8°C

These antibodies recognize Group A Streptococci. They do not cross-react with Streptococcus groups B through G, Streptococcus pneumoniae, Staphylococcus aureus, Corynebacterium dyptheriae, Streptococcus salivarius, or Micrococcus mucilagines.

Streptococcus pyogenes is the sole species of Lancefield group A and is often called group A streptococcus (GAS), because it displays streptococcal group A antigen on its cell wall. Infections due to certain strains of S. pyogenes can be associated with the release of bacterial toxins. Throat infections associated with release of certain toxins lead to scarlet fever. Other toxigenic S. pyogenes infections may lead to streptococcal toxic shock syndrome, which can be life-threatening. S. pyogenes can also cause disease in the form of postinfectious syndromes. These autoimmune-mediated complications follow a small percentage of infections and include rheumatic fever and acute postinfectious glomerulonephritis.